Can we measure built up stresses on the plate boundaries?

 Plate tectonics and internal built up stress

As it is believed that ,the Earthquakes occur due to built up stress on the plate boundaries.  As the moving plates  creates and built up stresses over plate boundaries.
When these built up stresses exceed the threshold limit ,the plates move one over other or side by side and hence a quake
Now being an engineer, I have some questions about these stresses.
Most of the major and devastating quakes occurs at shallow depth of 10 to 15 km.
Look at here ,what all data we have
1) plate area in sq kms
2) Depth of plates
3) Average density of plate
4) Hence mass of plates
5) speed of plates in cms per year etc
6) Hence kinetic energy a plate carry while moving say 1/2 mv2
7) we can drill up to 12 kms inside the Earth and can collect samples from depth.
8) We can test these samples taken from along plate boundaries and test them in Laboratory for compression, tensile and shear strength.
Now with all these data can seismologist find out the built up stress at 12 km depth?
Also can seismologist compare these built up stress with laboratory results
Keeping some factor of safety can seismologist predict when the built up stress will exceed laboratory results?
SO CAN WE PREDICT MAJOR EARTHQUAKES?